Ireland will be without Iain Henderson for their home clash with Italy in the Six Nations after he tested positive for coronavirus.
Andy Farrell’s side sit third in the table after a 29-7 triumph over Wales preceded a 30-24 loss to leaders France in the second round.
Ireland host winless Italy at the Aviva Stadium in Dublin on Sunday, but they will not have second rower Henderson to call upon after confirming the 30-year-old has contracted the virus.
Another spell on the sidelines will frustrate the Ulster captain, given he only returned from injury off the bench in the loss against France.
Henderson, who captained his country for the first time in February 2021, will now serve a period of self-isolation at home and will likely return for meetings with England and Scotland in March.
Ireland confirmed there were no other positive results within the squad and the group will continue to complete routine tests across the week.
Farrell will still have Tadhg Beirne, James Ryan, Kieran Treadwell and Ryan Baird as second-row options and has not yet called up a replacement for Henderson.