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Jamie George will miss England’s November internationals after he was ruled out for 10 weeks with a foot injury.
The hooker will be sidelined until early in December due to damage done in Saracens’ Premiership win over Leicester Tigers last Saturday.
George will play no part in the Red Rose’s Tests against Argentina, Japan, New Zealand and South Africa.
Eddie Jones had already lost Leicester centre Guy Porter and Harlequins hooker Jack Walker to injury.
Courtney Lawes, Sam Underhill, Anthony Watson, Maro Itoje and Alex Dombrandt are among the other England players who are unavailable due to injury.