Leicester second-rower Ollie Chessum will make his first start and Danny Care returns to Eddie Jones’ XV for England in the deciding third Test against Australia.
The tourists have made minimal changes to the side that delivered a major victory in Brisbane last Saturday, to force their three-game series to a decider against the Wallabies.
After overcoming the frustrations of an opening loss to their hosts in Perth despite a man advantage for most of the game, coach Jones rung the changes in a bid to stave off a second defeat in as many games.
That delivered a crucial 25-17 victory at Suncorp Stadium to take the series through to its final match, at Sydney Cricket Ground this weekend.
Chessum comes into the side as part of an enforced change, taking the spot of Maro Itoje, while Lewis Ludlum also steps up after Sam Underhill was ruled out with concussion.
Care meanwhile is the lone tactical change made by Jones to his backline, with the Harlequins scrum-half given the nod over Jack van Poortvliet, having been dropped for the latter in Queensland.
Australia meanwhile make four changes to the side that were downed in the Sunshine State, with two-time NRL premier and cross-code recruit Suliasi Vunivalu in line for a debut off the bench.
The ex-Melbourne Storm flyer switched codes to play for the Reds in 2021, and is the unfamiliar face among the newcomers, with Reece Hodge and Harry Wilson in for their first Tests of the year.
Nick Frost meanwhile gets a start in the second row and James Slipper moves back to the traditional spot of loosehead prop.
Australia team: Hodge, Wright, Paisami, Kerevi, Koroibete, Lolesio, White; Slipper, Porecki, Tupou, Frost, Philip, Wilson, Hooper, Valetini.
Replacements: Faingaa, Bell, Alaalatoa, Leota, Samu, McDermott, Ikitau, Vunivalu.
England team: Steward, Nowell, Porter, Farrell, Freeman, Smith, Care; Genge, George, Stuart, Chessum, Hill, Lawes, Ludlam, Vunipola.
Replacements: Cowan-Dickie, Vunipola, Heyes, Isiekwe, Willis, Van Poortvliet, Joseph, Arundell.