Neymar was named on the substitutes’ bench for Paris Saint-Germain’s Champions League last-16 first leg against Real Madrid, who were able to welcome back top scorer Karim Benzema on Tuesday.
Brazil star Neymar, who turned 30 earlier this month, has not played since suffering an ankle ligament injury in a win over Saint-Etienne in November.
However, he returned to training over the past week and was deemed fit enough by boss Mauricio Pochettino to be named on the bench for the visit of Los Blancos.
Lionel Messi, who scored 26 goals in 45 appearances against Madrid for Barcelona, Kylian Mbappe and Angel Di Maria lead the line for the Ligue 1 leaders.
Madrid, meanwhile, were able to call upon the services of talisman Benzema, who had not played since suffering a hamstring strain on January 23 against Elche.
Speaking on Monday, Los Blancos coach Carlo Ancelotti was non-committal on the availability of Benzema, but the France striker has been deemed fit enough to start in a huge boost for Madrid.
Benzema was named in attack alongside Vinicius Junior and Marco Asensio.