James Bhatti has withdrawn from Scotland’s squad for their opening Six Nations match, while Gregor Townsend will also be without Josh Bayliss.
Scotland face England in their first game of the tournament at Murrayfield on Saturday.
However, Bhatti, a loosehead at Glasgow Warriors, has withdrawn from the squad due to injury.
Bayliss, meanwhile, will remain with his club side Bath for further assessment after he suffered a concussion against Leinster in the Champions Cup on January 22.
Scotland’s update also confirmed Duhan van der Merwe and Kyle Rowe had joined up with the squad and that Sean Maitland, who was not selected by Townsend but was with the group, has returned to Saracens.
After hosting England, Scotland face Wales in Cardiff and then welcome France to Murrayfield before taking on Italy. They round off their campaign against Ireland in Dublin on March 19.