Harry Cardwell struck a late winner as Southend came from behind to beat the 10 men of Wealdstone 2-1.
Charles Clayden put the visitors in front midway through the first half, flicking home a cross from Dominic Hutchinson.
But Wesley Fonguck levelled early in the second half, collecting a loose ball and bending it into the net.
Things got worse for Wealdstone two minutes later when Nathan Ferguson was shown a straight red card.
And the extra man told with eight minutes to go when Cardwell turned in Noor Husin’s cross from close range.